Im now in my 40’s and have not worked out or taken P.E.D.

These results are yet to be replicated in human studies.

Muscle memory phenomenon can be largely explained by muscles maintaining their muscle nuclei during muscle loss or detraining.

The recent studies only counted the actual muscle nuclei and showed no loss. So researchers mistakenly assumed that the muscle nuclei die with muscle loss. In previous studies they were counting nuclei which belonged to the connective tissue and other cells (satellite cells). The recent studies used a different technique to study these nuclei. But why did we think muscle nuclei die with muscle loss? They know how much muscle you had before you stooped training. So these muscle nuclei seems to acts like ‘memory cells’. So what? Since now the muscle has the same number of muscle nuclei after we stopped training, it is easy to build the muscle back to its previous size. However, recently, studies using different animal models (denervation, unloading, synergic ablation) showed that as muscle atrophies or shrinks due to inactivity or detraining (until 3 months), there is no loss of muscle nuclei as we previously thought! As shown in the picture, the muscle size decreased by 50% (lines) but the muscle nuclie count (stained with green dye) remained the same. And this was supported in studies which showed as muscle shrinks in size, the number of nucleus decreases too. Just like muscle growth, we believed that when we lose muscle, the opposite happens - we lose some nuclei since there is no reason for the extra nuclei to sit around. It has been shown that people who take steroids and people who grow muscle easily have lot more muscle nuclei than normal. The increase in nucleus with muscle growth has been shown in number of studies. So when your muscles get bigger, you have to add more muscle nucleus. So why do muscles need so many nuclei? The nucleus is basically what controls the cell and since your muscles are a lot lot bigger and way more complex than other cells in the body, one or two nuclei just cannot do the job. Unlike other cells, muscle cells have more than one nucleus (probably thousands). The nervous system mechanisms may explain the strength gains, but it doesn’t explain how you can gain back the muscle size so quickly.īut recent studies show that we may have finally solved the mystery of muscle memory How did they solve it? We used to believe this is largely due to the nervous system mechanisms. This phenomenon is called ‘ muscle memory’. However, if you start training back again, you gain the lost muscle or strength within a few weeks - as if the muscle remembers where you left off. It does not store any personal data.Muscle memory is what? We all know that if you lift weights and stop lifting for a few months (3-6 months), you will lose strength and muscle. The cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies. The cookie is used to store the user consent for the cookies in the category 'Performance'.

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Memoria muscular